Research Overview

Proteins are an incredible class of polymers. The precise sequence of amino acid monomers is rapidly biosynthesized and encodes the necessary information to transform the simple polymer chain into a folded functional biomacromolecule. Among many amazing properties, protein biopolymers can (1) possess spectacular strength, (2) function as reliable machines and catalysts, and (3) dynamically assemble and disassemble. Our research capitalizes on the diverse structure and function found in native proteins and seeks to engineer complementary functionality into novel protein-based materials. Through genetic and synthetic modifications, we aim to gain responsive control of protein assembly and activity. By developing new protein-based materials, we strive to create solutions to problems in biomedicine, biotechnology, and synthetic biology.